Pothos are great beginner plants and will grow in virtually any conditions. High light, low light, high humidity, low humidity. The only two environments they don't perform the best in is Direct Sunlight and freezing temperatures. You'll want to keep your pothos at least 6" away from any drafty cold windows and out of any windows that have more that 3 - 4 hours of direct sunlight. Water your Pothos weekly at average, but most importantly, allow your Pothos to dry out fully between waterings. To encourage larger foliage or faster growth, try replacing a bulb in a floor lamp or ceiling light with a 26 Watt Grow light.
Pothos will grow well with an all purpose Fertilizer such as Schultz All Purpose Plant food diluted in your watering can, and will love any added epiphyte fertilizer you'd like to give it. We recommend an orchid fertilizer spray on the foliage or Epiphyte Delight, one of our favorite Foliar Fertilizers.